13C MRS: An outstanding tool for metabolic studies
نویسندگان
چکیده
منابع مشابه
13C MRS studies of neuroenergetics and neurotransmitter cycling in humans.
In the last 25 years, (13)C MRS has been established as the only noninvasive method for the measurement of glutamate neurotransmission and cell-specific neuroenergetics. Although technically and experimentally challenging, (13)C MRS has already provided important new information on the relationship between neuroenergetics and neuronal function, the energy cost of brain function, the high neuron...
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Introduction Cardiac metabolism assessment with hyperpolarized 13C in pig models requires dedicated coils design capable to provide large sensitivity regions. This work presents a comparison between a quadrature birdcage coil and a circular coil both designed for hyperpolarized studies of the heart in large animal models with a clinical 3T scanner. The results are presented as Signal-to-Noise R...
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متن کاملProgress towards in vivo brain 13C-MRS in mice: Metabolic flux analysis in small tissue volumes.
The combination of dynamic 13C MRS data under infusion of 13C-labelled substrates and compartmental models of cerebral metabolism enabled in vivo measurement of metabolic fluxes with a quantitative and distinct determination of cellular-specific activities. The non-invasive nature and the chemical specificity of the 13C dynamic data obtained in those tracer experiments makes it an attractive ap...
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ژورنال
عنوان ژورنال: Concepts in Magnetic Resonance Part A
سال: 2005
ISSN: 1546-6086,1552-5023
DOI: 10.1002/cmr.a.20039